Our TDK topics
Development of analytical methods to determine drugs and drug metabolites.
Supervisor: PERJÉSI, Pál
Co-Supervisor: Dr. BOGNÁR, Gábor
In the course of the work, students will get acquainted with the chemical basics of drug metabolism and will be involved in the development or application of an analytical method for the determination of a drug compound and its metabolites.
Stereochemical study of biologically relevant reactions of chalcones and chalcone analogues
Supervisor: PERJÉSI, Pál
Co-Supervisor: Dr. BOGNÁR, Gábor
In the course of the work, the students get acquainted with the most important chemical reactions of chalcones and study the stereochemistry of the reactions of differently substituted derivatives using the example of a selected reaction.
Structure-activity relationships of reactions of chalcones and cylic chalcone analogues
Supervisor: PERJÉSI, Pál
Co-Supervisor: Dr. BOGNÁR, Gábor
In the course of the work, students get acquainted with the most important chemical reactions of chalcones and study the relationships of the chemical reactivity-biological effect of differently substituted derivatives using the example of a relevant reaction.
Study on kinetic and stereochemical aspects of GSH-conjugation reaction of chalcones and cyclic chalcone analogues.
Supervisor: PERJÉSI, Pál
Co-Supervisor: Dr. BOGNÁR, Gábor
In this work, students will learn about the mechanism of glutathione (GSH) conjugation reactions and study the kinetics and stereochemistry of spontaneous and enzyme-catalyzed reactions of compounds using the examples of some chalcone derivatives.
Determination of logP value of chalcone- and curcuminoid derivatives.
Supervisor: ROZMER, Zsuzsanna
Co-Supervisor: Dr. TYUKODI, Levente
Interaction of curcuminoids and chalcone analogues with cellular macromolecules.
Supervisor: ROZMER, Zsuzsanna
Investigation of permeability of chalcone- and curcuminoid derivatives
Supervisor: ROZMER, Zsuzsanna
Co-Supervisor: Dr. TYUKODI, Levente
Study on the effect of curcuminoid derivatives on enzyme activity
Supervisor: ROZMER, Zsuzsanna
Co-Supervisor: Dr. HARMATH, Lilla Édua
Study on the effect of curcuminoid derivatives ont he cell-cycle
Supervisor: ROZMER, Zsuzsanna
Co-Supervisor: Dr. FÜLÖPNÉ KISS, Edit
In vivo and in vitro non-enzymatic and enzymatic oxidation of phenolic compounds
Supervisor: ALMÁSI, Attila
Transportmechanisms and metabolism of drug molecules in the small intestine. Structure-activity relationships.
Supervisor: ALMÁSI, Attila
Co-Supervisor: Dr. KOVÁCS, Sára